IBS is a disease due to which patients find changes in bowel habits which might differ from mild to severe problems. There are no especially known causes of IBS because chronic diseases that do not result in risk to life, aren’t given high priority. This disorder is largely related to the malfunctioning of the large intestine, commonly referred to as the colon. Hence, the signs are based on this area, and are accepted as functional disorders. This simply implies that the conditions aren’t produced by a substantial physical problem, but are initiated by the improper performance of the intestine arising because of stress, strain and negative reactions demonstrated towards food and other materials.


Research studies show that IBS symptoms arise following gastroenteritis symptoms subside. Thus, there’s possibility of locating internal physical harm on the walls of the gut, which explains the occurrence of these signs in the body. The neuroendocrine system refers to the functioning mix of the endocrine system combined with the nervous system, which can be effectively covered and controlled by the central nervous system.

As IBS is directly linked to stress variable, researches have been conducted to detect the connection between the functioning of the digestive tract and the functioning of the endocrine system. The neuro endocrine system possesses complete control over the inner balance state of the human body. Hence, it’s closely linked with gain in the stress level of their human body.


Evidences of high levels of pressure on the hypothalmic-pituitary-adrenal area can largely influence the immunity of the human body. This explains the lean inflammation that’s frequently observed among IBS patients. Further, it’s observed that anxiety is the major reason for aggravated IBS in patients. Hence, it’s strongly advised that the patients practice the principles of stress management to be able to curb the symptoms of IBS.

As stress is mostly controlled by the secretion of hormones and the inner balance of the human body, it’s inferred that the nerves and the endocrine system are working towards suppression of IBS symptoms and returning a steady degree of balance within the body.

Hormonal Factor

Hormones assist in manipulation of the amount of chemicals, along with other specific fluids. They help in coping up and reacting to different situations posed by the surrounding. Tumors created by the neuroendocrine cells are known as Neuroendocrine tumors. These cells are characterized by the secretion of hormones. The neuroendocrine cells are part of a network that’s collectively referred to as the neuroendocrine system. Though the neuroendocrine tumors could be recognized in several different areas of the body also, it’s discovered that the digestive tract has it in maximum variety.

They’re blamed for many symptoms regarding Irritable Bowel Syndrome, such as wheezing, flushing of skin and diarrhoea. However, all tumors of the neuroendocrine cells can’t be accounted for hormone manufacturers. Only tumors which are tagged as “functioning” are capable of secreting hormones whereas the tumors that are incapable of hormone secretion are known as non-functioning or non-hormone secreting tumors.


The neuroendocrine system and hormone secretion are found to have many effects on IBS symptoms and severity levels. But because of lack of adequate research on IBS symptoms, many chances haven’t been found as yet. Many medical specialists and researchers are praying that when the mystery is solved, treatment for the symptoms of Irritable Bowel Syndrome can be set. But at present, we lack adequate information which could provide suggestions regarding the last treatments towards the syndrome.