SLE is a chronic disease that causes inflammation of connective tissue. It’s a multisystem autoimmune inflammatory disorder. SLE is the commonest and the most serious type of lupus. SLE is thought to be an autoimmune disorder, meaning that the body’s immune system produce antibodies that strikes your body’s healthy organs.

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Besides, genetic predisposition may be among the causes. What are the risk factors for SLE? Females are more likely to acquire SLE than males. Usually the age of the individual is different between 15-45 years old. SLE is more common in dark races. Besides certain medications can trigger lupus. What are the medications that are associated with lupus? These drugs were associated with lupus just after long-term usage.

Chlorpromazine, Hydralazine, Isoniazid, Methyldopa, Procainamide, Quinidine. What are the symptoms of systemic lupus erythematosus (SLE)? 90 percent of patients will complain of joint arthritis and symptoms. This may be the earliest manifestation of this disease. Eye affection can happen in the kind of conjunctivitis, photophobia and blurring of vision. Systemic symptoms such as fever, malaise, anorexia and weight loss/gain are often present. Shortness of breath, chest pains, mouth sores, kidney acts affection that may result in renal failure.

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What’s SLE diagnosed? What’s the treatment of systemic lupus erythematosus? There’s no definitive cure for lupus until today. Drugs as nonsteroidal anti inflammatory drugs (NSAIDs) and corticosteroids are utilised to decrease the inflammation and pain. Anti-malarial drugs, as Hydroxychloroquine, had demonstrated to control the symptoms and signs of this disease and may prevent flares.

Immunosuppressive drugs, as cyclophosphamide, can be used particularly when there is kidney affection. This group of drugs have to be taken with extreme care. A whole lot of clinical research has been conducted by using new emerging drugs that could help treat SLE. Epratuzumab, a humanised IgG1 monoclonal antibody, entered phase III trials after promising results in a smaller study.

Avoid excessive exposure to sunlight by using sunscreens. Quit smoking and alcohol consumption. If you are taking immunosuppressive medication, then you shouldn’t take a live vaccine. At any time, if you experience severe acute symptoms or fever or anginal pains or shortness of breath, immediately call your physician. I hope this article was valuable to you. And I hope you stay healthy and happy forever.Thank you for reading.