Progressive systemic sclerosis (PSS) is a disorder that can affect many regions of the body. It’s characterized by the deposition of excessive amounts of connective tissue in the skin and internal organs in addition to immune abnormalities. The cause of PSS, like many other similar conditions is unclear.

PPS

Many environmental factors may cause the development of PSS and the genetic predisposition of every individual person might ascertain whether these environmental influences contribute to the evolution of the disease. It’s long been theorized that infections – both viral and bacterial – could act as triggers for PSS. In certain patients, antibiotic therapy relieves a number of the indicators of PSS. H pylori infection has recently received quite a great deal of attention concerning the development of PSS.

One study reported that the incidence of H pylori infection in PSS patients was significantly higher than in controls. However other studies haven’t reported these differences. It might be that not all H pylori strains create the very same responses in patients. For example, a further study revealed that 90 percent of PSS patients were infected with the CagA strain of H pylori. This specific strain appears to correlate with several different disease progressions, including heart disease and stomach cancer.

Take into account

Unfortunately there’s a scarcity of information from the literature in this area, but since H pylori infection has the capacity to activate a whole-body, or systemic inflammatory reaction, its role in diseases like PSS can’t be discounted and the role of CagA breeds should be researched further. As I have explained in a number of my posts, H pylori is one of several triggers that may result in a cascade of events inside the body that ultimately result in inflammatory and immune-mediated problems.

So I’d recommend that if you have any skin disease or autoimmune condition, you seek advice about the best way best to assess for all these probable triggers. Food allergies, hidden gastrointestinal infections such as H pylori, parasites, fungal overgrowth, nutritional deficiencies – particularly vitamin D in autoimmune disease – hormonal imbalances, accumulation of toxins in the body, poor liver function and several other imbalances may result in the inflammation cascade that ultimately leads to autoimmune diseases such as PSS.

Conclusion

At the same time, care must be taken to eliminate foods that may trigger inflammation in the gut. Of main concern are gluten, cow’s milk, soy, sugar and processed foods. Tools are available for you to check for digestive ailments, toxicity, food and chemical sensitivity and it’s these analyses that can allow you to discover the reason why your condition developed. Autoimmune conditions like PSS can be defeated, but it requires effort and comprehension of what’s causing them in the first location.


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